Labrador Retriever Genetic Tests
Below is the Introduction ONLY of what is being done. Use this link to read the full services they are providing:
CNM | HNPK | HUU
Centronuclear myopathy (CNM) is a naturally occurring, hereditary myopathy of Labrador Retrievers resulting from a mutation in the protein tyrosine phosphatase-like member A gene (PTPLA). This condition is also known as: type II muscle fiber deficiency, autosomal recessive muscular dystrophy and hereditary myopathy. The disease is inherited in an autosomal recessive fashion with both sexes being equally affected. CNM typically manifests in puppies at 2-5 months. Signs of CNM include: generalized loss of muscle tone and control, exercise intolerance and an awkward gait. Dogs with one normal copy and one mutant copy of the gene do not display signs. Breeding two carriers is predicted to produce 25% affected offspring and 50% carriers of the disease.
The VGL offers a DNA test for CNM to assist owners and breeders in identifying affected and carrier dogs. The test uses DNA collected from buccal (cheek) swabs, thus avoiding blood sample collection. Breeders can use results from the test as a tool for selection of mating pairs to avoid producing affected dogs.
One other link for CNM information:
They are no, longer performing this testing, BUT they have links to other info on this page supporting CNM.