Efficacy of liquid sildenafil as a novel treatment for canine generalized megaesophagus: a randomized crossover study
Purpose of Study
This study is designed to assess if the drug sildenafil could work to relax the lower esophageal sphincter in dogs, allowing food to pass more easily from the esophagus into the stomach. This would potentially reduce the frequency of regurgitation, allowing dogs to have better quality of life, reduced risk of aspiration pneumonia, and lower rates of death/euthanasia.