This is an abstract ONLY and after seeing it on VIN, decided to place it here for discussion with your veterinarian if interested.

The use of botulinum toxin for the treatment of generalized myoclonus in a dog.

J Am Anim Hosp Assoc. 2013 Mar-Apr;49(2):122-7.
DOI: 10.5326/JAAHA-MS-5786
Tom Schubert 1, Roger Clemmons, Sarita Miles, William Draper
1 Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
Companion Notes

Article Abstract

A 13 mo old spayed female mixed-breed dog presented in a nonambulatory state that was attributed to severe myoclonus secondary to distemper. The authors hypothesized that mitigating the myoclonus would help the dog become ambulatory and expedite convalescence. They injected the severely affected muscles with botulinum toxin on two separate occasions over a period of 18 days. Those injections reduced the myoclonus, helping the dog become ambulatory and attaining a comfortable, functional state.

Botox can be ordered from the company in California
( Allergan 1-800-433-8871 ) and obtain one vial that can be used and frozen for repeat use. The cost is approv $550 per vial,at least as of about 1 year ago.